AKT1 and Intervertebral disk degeneration: Meanwhile, the core targets were subjected to the KEGG pathway enrichment analysis to screen for pathways with P < 0.05, and a total of six were obtained, such as the PI3K-Akt signaling pathway, the thyroid hormone signaling pathway, the Notch signaling pathway, the FoxO signaling pathway, the estrogen signaling pathway, and the HIF-1 signaling pathway (Figure 7), among which the specific mechanism of deer antler treating intervertebral disc degeneration in the PI3K-AKT signaling pathway is shown in Figure 8.