CTRB2 showed significant sTWAS associations with T2D and T1D (Additional file 9: Table S8), and our fine-mapped sQTLs pointed to the same lead candidate causal variant, rs72802342, which appeared to cause a complete exon-skipping event in CTRB2 transcripts (Additional file 1: Fig. S9e). Here, CTRB2 is linked to type 2 diabetes mellitus.