The neoplastic TGF-β concentration in Rg3-Lp and Rg3-Lp/DTX group was nearly half of that in C-Lp/DTX group and consequently, the a-SMA gene expression of tumor tissues in Rg3-Lp and Rg3-Lp/DTX group was decreased to one-third of that in C-Lp/DTX group (Fig. 5E, F). This evidence concerns the gene SMN1 and neoplasm.