CCL7 and atherosclerosis: While the detailed pathological role of CCL7 and related signaling pathways in these diseases need further confirmation, it has been suggested that CCL7 may promote the progression of atherosclerosis and aortic aneurysm and play a significant role in the inflammatory events underlying most vascular diseases, DM, and kidney disease by attracting macrophages and monocytes to amplify inflammatory processes and contribute to the disease progression (Fig. 1).