The estimated dose-response curves for risk of anaemia in G6PD-deficient and normal young children (< 5 years old) from low-transmission intensity settings with a baseline parasitaemia of 10,000/μL with different baseline haemoglobin values are presented in Fig. 3 (see Additional file 3: Fig. S6 for other endpoints). The gene discussed is G6PD; the disease is anemia.