Although our study found an increased risk of anaemia in 194 G6PD-deficient individuals who received SD primaquine, haemoglobin dropped below 7g/dL (Hb0 − Hb7: 8.2–6.8, 8.8–6.0 g/dL) in only two patients, and serious adverse haematological events were few and transitory. This evidence concerns the gene G6PD and anemia (phenotype).