The hazard ratio for the highest versus lowest quarters was 1.28 (95% CI, 1.15–1.43) for TG and the lowest versus the highest quarters was 1.27 (95% CI, 1.14–1.41) for HDL-C, after adjustment for sex, age, smoking status, IMD tenth, BMI, SBP, eGFR, prior diabetes mellitus, prior CVD, antihypertensive medication, insulin, and statin use, at baseline. This evidence concerns the gene INS and diabetes mellitus.