Among the pairwise comparisons (tested using pairwise Wilcoxon rank-sum tests), IDC regions had significantly higher FOXP3+ and CA9+ colocalization, compared to synchronous DCIS regions (p = 0.0004) and pure DCIS samples (p = 0.0007) (Table 6). This evidence concerns the gene FOXP3 and ductal breast carcinoma in situ.