CD24 and neoplasm: Therefore, Barkal et al. used the single-cell RNA sequencing method to test the effects of CD24-Siglec-10 signaling cascade on macrophage-mediated tumor controlling ability within the tumor microenvironment, and they found the high expression of CD24 and Siglec-10 in several tumors that they analyzed at a cellular level which ultimately indicates the potential of CD24 as a tumor-specific marker [63].