We identified a genomic risk locus at HNF1B for diabetes (NC_000017.11:g.37741165C>G, rs7501939, p=6×10−17), increased ALT (NC_000017.11:g.37713312C>T, rs17138478, p=6×10−25), AST (NC_000017.11:g.37713312C>T, rs17138478, p=4×10−12) and GGT (NC_000017.11:g.37717101A>G, rs718961, p=2×10−52). Here, GPT is linked to diabetes mellitus.