C9 and age-related macular degeneration: Coding variants in these genes include the variants p. Gly119Arg (rs141853578) in CFI, p.Arg102Gly (rs2230199) and p. Lys155Gln (rs147859257) in C3, and Pro167Ser (rs34882957) in C9, which are associated with an increased risk of AMD.