EIF2AK4 and neoplasm: However, consumption of EAA-supplemented water by GCN2 KO-tumor bearing mice provided for increased tumor growth approaching that of wild-type GCN2 tumors, albeit there was a time delay of 20 days for 22Rv1 with wild-type GCN2 to about 40 days with EAA-supplemented GCN2 KO (Figure 6G).