To examine the role of TSLP in melanoma, we generated Tyr:Cre-ERT2(Tg/0)BrafLSL–V600E/+Ptenlox/lox mice by breeding Tyr:Cre-ERT2(tg/0)BrafLSL–V600E/+ (16) with Ptenlox/lox mice (22). This evidence concerns the gene MAPK3 and melanoma.