Among PLWH, C-reactive protein (CRP) was the first inexpensive, immediate, and effective screening test for TB (sensitivity ≥ 90% and specificity ≥ 70%) that met World Health Organization (WHO) requirements.[12] It is a nonspecific marker of the acute phase of the systemic inflammatory response, which can be measured using finger-prick blood collection. This evidence concerns the gene CRP and tuberculosis.