CRP and osteosarcoma: Li et al[19] analyzed 216 osteosarcoma patients and found that the OS rate of the high CRP/Alb group (>0.210) was significantly lower than that of the low CRP/Alb group (<0.210) and that CRP/Alb was an independent factor affecting the prognosis of patients with osteosarcoma (HR = 2.21, 95% CI = 1.40–3.49; P = .001).