DES and neoplasm: In addition, CAF is rich in small and medium-size blood vessels with thickened and hyaline walls and the interstitium has scattered collagen cellulose of varying thickness, which may show myxoid degeneration and edema.[18] Immunohistochemistry findings are important for the diagnosis of CAF.[18] CAF tumor cells exhibit diffusive and strong positivity for Vim, diffusive positivity for CD34, partial positivity for smooth actin (SMA), and negativity for Desmin (S-100).[24] The pathological features and immunohistochemistry of the present case were consistent with previous reports.