VEGFA and colorectal carcinoma: Shin et al reported that liver abscesses developed within necrotic areas after sorafenib treatment for multiple HCCs with portal vein tumor thrombosis.[10] There is a case report of liver abscess development after chemotherapy with bevacizumab, capecitabine, and oxaliplatin for colorectal carcinoma with liver and lung metastases.[11] In this patient, bevacizumab, a vascular endothelial growth factor inhibitor, inhibited tumor angiogenesis, resulting in tumor necrosis and an anaerobic environment that facilitated the proliferation of anaerobic bacteria, leading to liver abscesses.