Compared with gemcitabine/paclitaxel alone, NLR attenuation with anti-Ly6G improved chemosensitivity as evidenced by significantly decreased tumor area by H&E staining (p=0.01; Figure 2C) as well as increased cleaved caspase-3 and microvessel (CD31) density (Figure 2D) in gemcitabine/paclitaxel +anti-Ly6G treated mice compared with all other treatment groups. The gene discussed is CASP3; the disease is neoplasm.