ABHD5 and ichthyosis: Chanarin–Dorfman syndrome (CDS) is a neutral lipid storage disease with ichthyosis caused by homozygous mutations in α/β hydrolase domain containing 5 (ABHD5) gene, also known as comparative gene identification-58 (CGI-58) (Schweiger et al., 2009; Grabner et al., 2021).