Compared with EBV DNA, low level of TEP lncRNA ROR correlated well with positive EBV DNA, TEP lncRNA ROR and EBV DNA had similar diagnostic positive rate (58.3%) for NPC, and the combination of TEP lncRNA ROR and EBV DNA increased the positive rate to 74%. The gene discussed is LINC-ROR; the disease is nasopharyngeal carcinoma.