Laser photocoagulation to ablate the peripheral retina reduces ischemic drive for neovascularization; as in AMD, anti-VEGF therapy prevents vascular leakage, and chronic steroid supplementation can also help (Patel et al. 2008; Adamis et al. 1994; Wilkinson et al. 2003). Here, VEGFA is linked to age-related macular degeneration.