ACE and diabetes mellitus: Included: untreated OSA, all subjects were overweight (BMI 38.0 ± 5.1), snored, excessive daytime sleepiness, medications wer enot withheld or changed during the study period. Subject characteristics: 1× noninsulin-dependent DM and treated with oral hypoglycemic agent. 2× hypertensive treated with an angiotensin-converting enzyme inhibitor.