NLRP3 and infection: It can induce a type I IFN response in a STING-dependent manner, trigger the NF-κB pathway by activating ERAdP or inhibiting RECON, induce an NLRP3-dependent inflammasome response, and activate host cell autophagy, promoting the production and secretion of signaling mediators such as cytokines, thus modulating the host defense against infection.