SIRT1 and brain ischemia: The fermented Chinese formula Shuan-Tong-Ling, including Codonopsis Radix, Macrocephalae Rhizoma, Radix Bupleuri, Paeoniae Radix Alba, Astmgali Radix, and so on, protected against cerebral ischemia/reperfusion injury by reducing inflammation and apoptosis through activation of the SIRT1 signaling pathway [45].