ST6GAL1 and colorectal carcinoma: These findings in drug resistant cells were augmented by a recent study concluding that EGFR is indeed α2,6 sialylated by ST6Gal1 in a glycosite specific fashion: this modification of EGFR was, in part, responsible for resistance to cetuximab induced cytotoxicity in CRC (Rodrigues et al., 2021).