The relationship of ST6Gal1 to VEGF was also determined in non-small cell lung cancer cells in which ST6Gal1 downregulation caused Notch1 pathway disruption and subsequently decreased protein expression of VEGF along with MMP-2, MMP-7 and MMP9: this resulted in reduced proliferation, migration and invasion (Sartakhti et al, 2017). Here, VEGFA is linked to non-small cell lung carcinoma.