AXIN1 and neoplasm: The deregulation of critical Wnt pathway-associated proteins such as catenin β1 (CTNNB1), axis inhibition protein 1 (AXIN1), casein kinase 1α (CSNK1A1), glycogen synthase kinase 3 β (GSK3β), and T-cell factor 4 (TCF4) can eventually affect tumor cell invasion and pathways correlated with malignancies (Qiu et al., 2019).