According to the Diao et al. (2019a) reported study, the lncRNA ZEB2-AS1 is an essential mediator of in vitro EMT induction in response to TGF-β1, with the silencing of ZEB2-AS1 resulting in the ZEB2 mRNA stabilization that ultimately suppresses the ability of HNSCC cells to proliferate, invade, and metastasize. This evidence concerns the gene TGFB1 and head and neck squamous cell carcinoma.