Similar to how the FTH1P3 lncRNA modulates PI3K/Akt/GSK3β/Wnt/β-catenin signaling to promote oncogenesis, LOLA1 (lncRNA oral leukoplakia progressed associated 1) can influence AKT/GSK‐3β signaling to assist the EMT induction (Liu et al., 2018a). This evidence concerns the gene GSK3B and leukoplakia.