The STAT3-induced upregulation of HNF1A antisense RNA 1lncRNA (HNF1A-AS1) can promote the Notch pathway activation and OSCC progression via HES-1, with HNF1A-AS1 also offering significance as a prognostic biomarker in patients with this carcinoma (Liu et al., 2019). This evidence concerns the gene HNF1A and carcinoma.