DNMT3A and neoplasm: The results showed that the high-risk group had higher enrichment for hypoxia, EMT, Cancer_m6A_modification, DDR, DNA replication, antigen processing and presenting machinery (APM) signatures, whereas the low-risk group was mainly enriched for aspects of the immune system and tumor cell growth suppression, such as PAN_F_TBRs, immune checkpoints, TNF family members receptors and ferroptosis(Figure 7D).