CAMP and chronic obstructive pulmonary disease: In this study we show that a trimeric recombinant fragment of SP-A is sufficient to neutralize the cytotoxic and proinflammatory effects of cathelicidin in alveolar epithelial cells, without affecting the microbicidal activity of LL-37 against K. pneumoniae, nontypeable H. influenzae, and P. aeruginosa, which can exacerbate COPD, asthma, and lung fibrosis and induce airway attacks in immunocompromised patients and the aged (88).