The major DEGs for the three distinct quiescent AM clusters (Mo/Ma 0, 1 and 3) were mostly associated with regulation of inflammation.Cluster Mo/Ma 0 (FABP5high AMs) overexpressed OLFM4, FAPB5 and ANXA2. OLFM4, a marker of severe lung disease, may be involved in the inflammatory response regulation (64, 65). The gene discussed is OLFM4; the disease is lung disorder.