LCMV-Arm viral titer was significantly high on day 8th post-infection in the serum of Cd47−/− mice, indicating that CD47 is necessary for resolving the acute viral infection.28 We saw an exponential expansion of CD8+ T cells in the spleens of infected mice; however, no significant difference was observed between CD47-sufficient and deficient groups. This evidence concerns the gene CD47 and infection.