Using expression data mined from five GEO databases, we verified the differential expression of COL10A1 in PAAD (GSE15471: p = 2.9  e − 11; GSE101448: p = 9.3  e − 07; GSE62165: p = 6.6 e − 09; GSE16515: p = 1.1 e − 05; GSE62452 : p = 4.2  e – 13; Figures 1(c)–1(g)). The gene discussed is COL10A1; the disease is pancreatic adenocarcinoma.