SSPOP and scoliosis: Rather, ciliogenesis defects in the developing forebrain, and rhombencephalic ChPs of katnb1mh102/mh102 mutants were found to correlate temporally with CSF flow defects and scoliosis onset, suggesting that the primary deficit in katnb1 IS models may relate to abnormal ChP development and/or function—a model supported by ectopic aggregations of Sspo protein localized specifically below fChP and rChP in katnb1mh102/mh102 mutants.