The expression pattern of 21 m6A genes (m6A writers: METTL3, METTL14, WTAP, ZC3H13, and RBM15/15B; m6A erasers: ALKBH5 and FTO; and m6A readers: YTHDC1/2, YTHDF1/2/3, CBLL1, HNRNPC/A2B1, FMR1, LRPPRC, RBMX, ELAV1, and IGF2BP1) in healthy and AD samples was investigated in GSE52093, GSE98770, GSE147026, and GSE153434 datasets. This evidence concerns the gene YTHDF1 and Alzheimer disease.