PCNA and neoplasm: We also examined the protein level of tumor tissues in two groups, which showed that PHGDH and pathway-related indicators β-catenin, c-myc, cyclin D1, PCNA, Bcl2, N-cadherin, vimentin, and Snail expression level were lower and BAX and E-cadherin higher in CBR-5884 group (Figure 6(d)).