The expression of several sPLA2s is altered in various cancer cells, and in the neighboring stromal and immune cells at primary or metastatic tumor sites (Cummings, 2007; Murakami et al., 2011; Brglez et al., 2014; Sukocheva et al., 2019; Scott et al., 2021). This evidence concerns the gene PLA2G2D and metastatic neoplasm.