Consequently, MMP1 protein abundance could be categorized into low (40) or high expression (63) in HNSCC samples while negative (6), low (8), or high expression (6) in normal oral epithelial samples, which suggested that MMP1 was abnormally overexpressed in HNSCC (P < 0.0001, chi-square test). The gene discussed is MMP1; the disease is head and neck squamous cell carcinoma.