The data suggests that MMP1 correlated genes enriched in numerous cancer-related biofunction and pathways such as wound healing, cell-substrate adhesion, cell-matrix adhesion, PI3K-Akt signaling pathway, human papillomavirus infection, focal adhesion, MAPK signaling pathway, and proteoglycans in cancer, indicating MMP1 played a pro-tumorigenic role by these pathways (Figure S3B, C). Here, AKT1 is linked to human papilloma virus infection.