MMP1 and head and neck squamous cell carcinoma: Moreover, the similar conclusion from GSE41613, GSE42743, and TCGA-HNSCC cohort also showed that overexpression of MMP1 had reduced overall survival compared to low MMP1 expression (Log-rank, P =0.031, 0.0526, 0,046, Figures 3(c) and 3(d) and Figure S2A).