Among those screened lipids, the levels of Cer (N24:0, N23:0 and N22:0), SM (N22:1 and N20:0) were positively correlated with IL-1β level and arthritis score, as were the total amounts of SM species and Cer species; while LysoPC (20:4 and 18:0) and the total amount of LysoPC species were negatively correlated with IL-1β and arthritis score. Here, IL1B is linked to Arthritis.