Studies have shown that the virgin olive oil and lemon volatile oil can reduce the AchE enzyme activity and MDA level in the hippocampus of mice with stress injury to a certain extent, increase the activity of SOD and GSH-Px, improve the learning and memory abilities of mice, and prevent AD (Falls et al., 2018; Tzekaki et al., 2021). The gene discussed is ACHE; the disease is Alzheimer disease.