Decreasing the mRNA expression level and serum concentration of inflammatory cytokines such as TNF-αIL-6, and IL-1β, suppressing the p-NFκB protein over-expression, up-regulating protein expression of p-Akt and GLUT2 in a rat model of insulin resistance Shi et al. (2022). The gene discussed is NFKB1; the disease is Insulin resistance.