Mi et al. (2020) found that roxadustat reduced the abnormal accumulation of lipids in cells and zebrafish that had a deficient ATP7B gene. Hasegawa et al. (2020) showed that HIF stabilizers counteracted the altered renal energy metabolism that occurs during diabetic nephropathy by downregulating fatty acid and amino acid metabolism and upregulating glycolysis, effects may inhibit the progression of diabetic kidney disease (DKD). The gene discussed is ATP7B; the disease is diabetic kidney disease.