For example, the increased abundance of Prevotella has been linked with periodontitis, augmented T helper type 17 (Th17) ‐mediated mucosal inflammation, rheumatoid arthritis, inflammatory autoimmune diseases, metabolic disorders, and low-grade systemic inflammation (Larsen, 2017; Tett et al., 2021), suggesting the inflammatory properties of Prevotella. OSA is associated with the occurrence of intermittent hypoxia and fragmented sleep, which could lead to oxidative stress and low-grade inflammatory responses (Tan et al., 2013; Cai et al., 2021). The gene discussed is SGCG; the disease is metabolic disease.