The correlation between the expression level of CDK2AP1 and neoantigens was performed, which indicated that CDK2AP1 expression was significant related to neoantigens in GBM (p = 0.019), BRCA (p = 9.2e-06) and rectum adenocarcinoma (READ) (p = 0.00021) (Figure 3A). The gene discussed is CDK2AP1; the disease is glioblastoma.