Recent studies have shown that TGFB2 expression is upregulated in gastric cancer, non–small cell lung cancer, gallbladder cancer, colorectal carcinoma, and high-grade glioma, which is associated with poor prognosis (Bogdahn et al., 2011; Zhang et al., 2020; Liao et al., 2021; Song and Zhou, 2021). This evidence concerns the gene TGFB2 and gallbladder cancer.