DTNA is a scaffold protein that maintains the structural integrity of the heart and skeletal muscle (Cao et al., 2017) and has been proven to predict the survival prognosis of bladder cancer (Zhang et al., 2021), hepatocellular carcinoma (Huang SN et al., 2020), gastric adenocarcinoma (Qin et al., 2019) and esophageal cancer (Fu et al., 2021). Here, DTNA is linked to esophageal cancer.