Recent studies have showed that SNHG12 can regulates the Wnt/β-catenin signaling pathway in papillary thyroid carcinoma cells to promote cellular proliferation and metastasis, but also plays a regulate the occurrence and development of glioma (Liu et al., 2018), osteosarcoma (Zhou et al., 2018) and gastric carcinoma (Yang et al., 2018). The gene discussed is SNHG12; the disease is osteosarcoma.