We constructed an mRNA–miRNA–lincRNA ceRNA interaction network centered on miR-22-3p and used the starBase v2.0 and miRWalk databases to predict eight related transcription factors associated with cardiovascular disease, namely, CTCF, JUN, JUND, NFATC1, NFE2L2, RAD21, RELA, and TAL1. Here, NFE2L2 is linked to cardiovascular disorder.