As shown in the picture, the expression of a large majority of cuproptosis-associated genes including FDX1, LIAS, LIPT1, DLD, DLAT, PDHA1, and PDHB was positively correlated with RNAss and DNAss, which indicated that the higher the levels of cuproptosis-associated genes are, the higher the levels of stem cell scores, the more vigorous the tumor stem cells, and the lower the levels of tumor differentiation. The gene discussed is PDHA1; the disease is neoplasm.