DLD and neoplasm: As shown in the picture, the expression of a large majority of cuproptosis-associated genes including FDX1, LIAS, LIPT1, DLD, DLAT, PDHA1, and PDHB was positively correlated with RNAss and DNAss, which indicated that the higher the levels of cuproptosis-associated genes are, the higher the levels of stem cell scores, the more vigorous the tumor stem cells, and the lower the levels of tumor differentiation.