FTO and obesity due to melanocortin 4 receptor deficiency: The mapped genes (FTO, SLC38A11, and RNA5SP111) of the identified PCOS SNPs in our study were also associated with obesity-related traits, including WHR, WHR adjusting for BMI, and childhood BMI (CBMI), suggesting the shared genetic architecture of PCOS, T2D, and obesity (Liu et al., 2022).