LINC01116 is oncogenic in several other kinds of tumors (Hu et al., 2018; Chen et al., 2020; Wu et al., 2020; Ye et al., 2020) and promotes lung adenocarcinoma proliferation and metastasis possibly via the Akt pathway (Zeng et al., 2020; Shang et al., 2021; Wu et al., 2021). Here, AKT1 is linked to lung adenocarcinoma.