As shown in Fig. 7A, infiltrating levels of cancer-associated fibroblasts (CAF) and macrophages were elevated in high SERPINH1 expression samples, whereas infiltrating levels of B cells, CD4+ T cells, and CD8+ T cells were downregulated in high SERPINH1 expression samples compared to low SERPINH1 expression samples. The gene discussed is CD8A; the disease is cancer.