Itkonen et al. (Itkonen et al. 2016) confirmed the anti-cancer roles of ST045849: They found that inhibition of intracellular OGT activity in prostate cancer cells by ST045849 resulted in complete depletion of intracellular alanine, thereby inhibiting cancer cell viability and growth rate, and continuously induced the death of prostate cancer cells. Here, OGT is linked to Familial prostate cancer.