This pattern was corroborated by Grimwade et al. [132] who observed that malaria incidence in persons with CD4+ T cell count ≥ 500/μl, between 200 and 499/μl and < 200/μl was 57, 93 and 140 per 1000 person-year, respectively, in Uganda. The gene discussed is CD4; the disease is malaria.